| abstract |
There are disclosed derivatives of avermectin compounds with a Δ26,27-alkyl chain of 4, 5 or 6 members at the 25-position. The compounds are prepared from the known Δ26,27-compounds by the appropriate synthetic procedures at the 5-, 8-, 9-, 13-, 22- and 23-positions. The compounds are potent antiparasitic agents, in particular, the compounds are anthelmintic, insecticidal and acaricidal agents. |