abstract |
4(3H)-Quinazolinone derivatives of formula (I) are provided.n wherein R₁ is a hydrogen atom, a C₁-C₆ alkyl group, an aryl group, a substituted aryl group, or an aralkyl group; R₂ is a C₁-C₆ alkylamino group, a phenyl group, a substituted phenyl group, or a 5- or 6-membered heterocyclic group containing one or more N, O or S as a hetero atom or atoms, said heterocyclic group optionally being substituted or fused with a benzene ring; n is 1 or 2; or R₂ represents a geranyl group or a dipyridylmethyl group together with the group -(CH₂) n -; and X is a hydrogen atom, a C₁-C₆ alkyl group or a halogen atom, and pharmaceutically acceptable acid addition salts thereof. n They are useful as antiulcer agents. |