| abstract |
New renin-inhibitory oligopeptides, their preparaton and their use. Oligopeptides of formula (I):n where R 1 -R 5 are various organic groups, and A represents a group of formula -NH-or -(CH 2 ) n -, in which n represents an integer of from 1 to 3, have renin-inhibitory activity and are particularly suitable for oral administration. They may be prepared by condensing their component amino acids or lower oligopeptides using conventional peptide synthesis reactions. |