http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0244359-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-56 |
| filingDate | 1987-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f396927d2bc81055cfc776e4d0484bd |
| publicationDate | 1987-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0244359-A2 |
| titleOfInvention | Process for the preparation of pyrimidine derivatives |
| abstract | There is a process for the preparation of 2-mercapto-4,6-bis-fluoroalkoxypyrimidines of the formula I <IMAGE> in which R1 C1-C4-alkyl, phenyl or benzyl and T1 and T2 independently of one another are each hydrogen, or a group-CHX1X2 mean in which X1 and X2 independently of one another represent trifluoromethyl, fluorine, chlorine or bromine. According to this process, 2-mercapto-4-halogen-6-hydroxypyrimidines of the formula <IMAGE> in which R1 has the meaning given above and Y is chlorine or bromine, with chlorodifluoromethane or a 1,1-difluoroalkene of the formula <IMAGE> in which X1 and Y1 each independently represent trifluoromethyl, fluorine, chlorine or bromine, in an inert solvent in the presence of a strong base to give a 2-mercapto-4-halogeno-6-fluoroalkoxypyrimidine of the formula VI <IMAGE> in which R1, Y and T1 have the meaning given above, converted this by further reaction with an alkali or alkaline earth metal nitrite into a 2-mercapto-4-hydroxy-6-fluoroalkoxypyrimidine of the formula <IMAGE> in which R1 and T1 have the meaning given above, and this then converted into a 2-mercapto-4,6-bis-fluoroalkoxypyrimidine of the above formula by reaction with chlorodifluoromethane or a 1,1-difluoroalkene of the above formula. The 2-mercapto-4,6-bis-fluoroalkoxypyrimidines of the above formula are intermediates for the preparation of herbicidally active sulfonylureas. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0375617-A1 |
| priorityDate | 1986-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.