| abstract |
A new process for the preparation of fluoroalkoxyaminopyrimidines of formula 1 where R is hydrogen. C 1 -C 4 alkyl, C 1 -C 4 -alkoxy or benzyl, X is halogen, C 1 -C 4 -Alkvl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkyl, C 1 -C 4 -haloalkoxy. C 1 -C 4 alkylamino or di-C 1 -C 4 alkylamino and T is hydrogen, chlorofluoromethyl, bromofluoromethyl, difluoromethyl or 1,2,2,2-tetrafluoroethyl, is characterized in that a thiopyrimidine of the formula II wherein Y has the meaning given to X for formula I or hydroxyl, A is hydrogen, sodium, potassium, or an equivalent of calcium or magnesium and Q is C 1 -C 4 -alkyl, phenyl or benzyl, with difluorochloromethane. Difluorobromomethane, tetrafluoroethylene, perfluoropropylene. Trifluoromethylene or Trifluorchloräthylen ems in the presence of a base, the compound of formula III obtained by oxidation into a compound of formula IV wherein n stands for the number one or two, and this compound with an amine of formula V treated |