| abstract |
Compounds of formula (I), and a pharmaceutically acceptable salts thereof:n wherein:n R, is hydrogen or CH 2 OH; R 2 is hydrogen or, (when R, is hydrogen), hydroxy or CH 2 OH; R 3 is CH 2 OH or, (when R, and R 2 are both hydrogen), CH(OH)CH 2 OH; R 4 is hydrogen, hydroxy, amino or OR 5 wherein R 5 is C 1-6 alkyl, phenyl or phenyl C 1-2 alkyl either of which phenyl moieties may be substituted by one or two halo, C 1-4 alkyl or C 1-4 alkoxy groups; and in which any OH groups in R,, R 2 and/or R 3 may be in the form of O-acyl, phosphate, cyclic acetal or cyclic carbonate derivatives thereof; having antiviral activity, processes and intermediates for their preparation and their use as pharmaceuticals. |