Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 |
filingDate |
1984-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ef9e11dcacbd4c69bb040cf12bff85a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab951e829a34b9b28a03fc5bc929f0f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_365bdf5c1e2ea3c8d3ee07d4dc3b8bc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c2d66a0fcf64c0fc060f69d3d91f60a |
publicationDate |
1985-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0130126-A1 |
titleOfInvention |
(S)-9-(2,3-dihydroxy-1-propoxymethyl) guanine and its acyl derivatives, their preparation and their application as antiherpetic agents |
abstract |
(S)-9-(2,3-dihydroxy-1-propoxymethyl)- guanine has potent antiherpetic activity which is superior to the corresponding racemic mixture or the (R)-enantiomer and also is much more potent than 9(2-hydroxyethoxymethyl)guanine. Acyl derivatives (prodrugs) of the (S)-enantiomer, which are more effective than the corresponding (R)-enantiomer analogs or related racemic mixtures provide formulation advantages and even higher plasma half lives in animals or man than the (S)-isomer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0242482-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0152316-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0393920-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9306112-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9403467-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9403467-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0161955-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6057305-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6653296-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0393920-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0242482-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5627185-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5216142-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4966895-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6479673-B1 |
priorityDate |
1983-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |