http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0236734-A3
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-86 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 |
| filingDate | 1987-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1988-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0236734-A3 |
| titleOfInvention | 5-Amino-4-hydroxyvaleryl derivatives substituted by s-containing groups |
| abstract | Compounds of the formula wherein R₁ by a thio, sulfinyl or sulfonyl group substituted acyl, A an optionally N-alkylated α-amino acid residue which is N-terminally connected to R₁ and C-terminally to the group -NR₂-, R₂ is hydrogen or lower alkyl, R₃ is hydrogen, lower alkyl, optionally etherified or esterified hydroxy-lower alkyl, cycloalkyl, cycloalkyl-lower alkyl, bicycloalkyl-lower alkyl, tri cycloalkyl-lower alkyl, aryl or aryl-lower alkyl, R₄ hydroxy, etherified or esterified hydroxy, R₅ lower alkyl, optionally etherified alkyl, cyclo-cyclo, bicyclo-alkyl, esterified cyclo, bicycloalkyl, esterified or cyclo-hydroxyalkyl, cycloalkyl-lower alkyl, tricycloalkyl, tricycloalkyl-lower alkyl, aryl, aryl-lower alkyl, optionally substituted carbamoyl, optionally substituted amino, optionally substituted hydroxyl or optionally substituted mercapto, sulfinyl or sulfonyl and R₆ substituted amino, and salts of such compounds with salt-forming compounds Groups inhibit the blood pressure-increasing effects of the enzyme renin and can be used as anti-hypertensives. |
| priorityDate | 1986-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.