| abstract |
The invention relates to new 6, 16-diamino-androstane derviatives of formula (I)n whereinn Y is hydrogen or an OAc group, Ac is an alkylcarbonyl group having from 1 to 4 carbon atoms in the alkyl moiety, A is methylene or a group of formula N-R 1 (wherein R 1 is alkyl having from 1 to 4 carbon atoms). B is methylene, or a group N-R 1 or N-R 2 , in which R 1 is as defined above and R 2 is a -CH 2 -CH 2 -COOR 1 , and n is 1 or 2, m is 1, 2 or 3, and physiologically acceptable diquaternary and monoquaternary salts thereof with C 1-4 alkyl or alkenyl groups. n Processes for preparing the compounds of formula (I) and compositions containing them are also disclosed. The compounds are potentially valuable as muscle relaxants. |