http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0204264-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
| filingDate | 1986-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f2d35660ec32e359b1cb487ea1946b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb00f7d504d05b0a13f99f103010d175 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d8c69c706ffd321f128eb629445d5a6 |
| publicationDate | 1986-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0204264-A2 |
| titleOfInvention | Conversion of uracil derivatives to cytosine derivatives |
| abstract | A process is disclosed for producing a 4-0-sulfonyluracil derivative of the formula[wherein R<sup>1</sup> is hydrogen, halogen, alkyl and alkoxy, R<sup>2</sup> is glycosyl having protected hydroxyls; and -SO<sub>2</sub>R<sup>3</sup> is an organic sulfonyl] which comprises reacting an uracil derivative of the formula[wherein R<sup>1</sup> and R<sup>2</sup> are the same above] with an organic sulfonylating agent of the formula R<sup>2</sup> S0<sub>2</sub>X [wherein R<sup>3</sup>S0<sub>2</sub> is an organic sulfonyl and X is halogen] in the presence of potassium carbonate. The obtained 4-0-sulfonyluracil is further subjected to amination. The processes are industrially advantageous and produce cytosine derivatives such as cytidine in high yield. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0757056-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101580528-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0630897-A2 |
| priorityDate | 1985-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 234.