| abstract |
Compounds of formula (I):n whereinn R 1 is halogen, alkyl or alkoxy; R 2 is hydrogen, halogen, alkyl or alkoxy; R 3 is an optionally substituted, saturated, unsaturated or aromatic, carbo- or hetero-, mono- or bi-cyclic group; R 4 is hydrogen or alkyl,n is located meta or para to the imidazolinylamino group; one of R 5 and R 6 is hydrogen and the other is hydrogen, alkyl or acyl; and N is 0, 1, 2 or 3, nor an acid addition salt thereof, have antidiarrhoeal activity. |