abstract |
A 3,5-di-tert-butylstyrene derivative represented by the general formula (1):n wherein R' stands for an acyloxy group represented by R 3 COO (R 3 is a hydrogen atom or an alkyl group with C, - C 6 ), an alkoxyl group of R 4 O (R 4 is an alkyl group with C, - C 4 ), a hydroxyl group, or a hydrogen atom; R 2 stands forn (R 5 is a hydrogen atom or an alkyl group with C 1 ~C 3 and X' is CH 2 or an oxygen atom),n (R 5 and X' are each the same as defined above), orn (X 2 is an oxygen or sulfur atom), and salts of its members capable of forming salts and processes for the preparation, and also a pharmaceutical composition comprising, as an active ingredient, the above compound in association with pharmaceutical excipients. |