| abstract |
The thioester of a-mercaptopropionylglycine with p-isobutylphenylpropionic acid simultaneously shows anti-inflammatory and mucolithic activities. It is prepared by reacting a reactive derivative of p-isobutylphenylpropionic acid and a-mercaptopropionylglycine at low temperature and in a polar solvent. The salts with organic and inorganic bases, with basic aminoacids and with basic antibiotics, are stable and generally water soluble, whereby the active principle of the invention car be formulated for oral, parenteral, rectal and topical administration. |