http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0024525-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ee5285e8e8edccb061046ff20da7a6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-64 |
| filingDate | 1980-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90c264e0a0d61edbe789f74eb3b1ad4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f42380f35711654c0791d7609dec357b |
| publicationDate | 1981-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0024525-A1 |
| titleOfInvention | Process for the preparation of luciferin and its derivatives |
| abstract | X eine OH-Gruppe und X 1 ein Wasserstoffatom oder eine OH-Gruppe bedeuten, insbesondere Luciferin, demethyliert man 2-Chlor-mono-bzw. -di-methoxybenzothiazol durch Umsetzen mitJodtrimethylsilan oder einer Mischung aus Phenyltrimethylsilan und Jod und durch Hydrolyse des gebildeten Silylderivats unter milden Bedingungen, wobei man vor oder nach der Einwirkung der Organosiliziumverbindung das Halogenatom in 2-Stellung gegen die Cyangruppe austauscht, und setzt das so erhaltene 2-Cyano-mono oder -dihydroxybenzothiazol mit D-Cystein um. For the preparation of compounds of the general formula wherein X is an OH group and X 1 represents a hydrogen atom or an OH group, in particular luciferin, demethylated 2-chloro-mono- or. -di-methoxybenzothiazole by reaction with iodotrimethylsilane or a mixture of phenyltrimethylsilane and iodine and by hydrolysis of the silyl derivative formed under mild conditions, the halogen atom being exchanged for the cyano group in the 2-position before or after the action of the organosilicon compound, and the resulting 2 -Cyano-mono or -dihydroxybenzothiazole with D-cysteine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5412625-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8702667-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5585247-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5696001-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5648229-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5424440-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5035999-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8805434-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0399409-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0399409-A3 |
| priorityDate | 1979-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.