| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 |
| filingDate |
2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2432444fb30589a7e99bd8bd5ef44e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a82b288d4285c71abd1507cf588d26f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b196d072e478983e0bcd89192f5954c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca522bcb5779e48c5bf8ccf0e0ab01ad |
| publicationDate |
2019-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EA-033284-B1 |
| titleOfInvention |
8- [6- [3- (AMINO) PROPOXY] -3-pyridyl] -1-isopropyl-imidazo [4,5-c] quinolin-2-one derivatives as selective kinetics modulators of an ataxia-atomic mutation kinase) CANCER TREATMENT |
| abstract |
The present invention generally relates to compounds of formula (I) and their pharmaceutically acceptable salts, where R, R, R, R and R have any meanings as defined herein. The invention also relates to the use of compounds of formula (I) and their salts for the treatment or prevention of diseases mediated by ATM, including cancer. The invention further relates to pharmaceutical compositions comprising substituted imidazo [4,5-c] quinolin-2-one compounds and pharmaceutically acceptable salts thereof; kits comprising such compounds and salts; methods for the production of such compounds and salts; and intermediates useful for such production. |
| priorityDate |
2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |