abstract |
The present invention belongs to the field of medical technology, and specifically relates to imidazoquinoline PI3K and mTOR dual inhibitors represented by general formula (I), pharmaceutically acceptable salts thereof or stereoisomers thereof: wherein R 1 , R 2 , R 3 , R 3 ′, R 4 , R 4 ′, R 5 and X are as defined in the description; the present invention also relates to the preparation methods of these compounds, the pharmaceutical preparations containing these compounds, and the preparation of these compounds for the treatment and/or Use in drugs for the prevention of proliferative diseases. |