abstract |
The invention describes bicyclic heterocycles of general formula (I) in which R, R, R, R and X have the meanings indicated in claim 1, their tautomers, their stereoisomers, their mixtures and their salts, especially their physiologically compatible salts with inorganic or organic acids, while such compounds have valuable pharmacological properties, primarily the inhibitory effect on signal transduction mediated by tyrosine kinases, and the use of these compounds for the treatment of various diseases, primarily of neoplastic diseases, as well as benign prostatic hyperplasia, diseases of the lungs and airways, and the preparation thereof. |