| abstract |
Aminoalkyl-substd. N-acryl-N-hydrocarbyl-benzocycloalkyl-amine derivs. of formula (I) and their acid addn. salts are new: m = 0-2; n = 2-4; R1 = H, 1-4C alkyl, Ph, halo, OH or 1-4C alkoxy (opt. substd. in the 2-, 3- or 4-position by NR4R5; R2 = H or 1-4C alkyl; R3 = <= 5C alkyl, alkenyl or alkynyl (with the double bond isolated from the C-N bond), phenyl (opt. substd. by 1-3 halo, 1-3C alkyl, OH, 1-3C alkoxy, NH2 and 1-3C acylamino), cyclohexyl, benzyl (opt. ring-substd. by 1 or 2 of 1-3C alkyl, OH, 1-3C alkoxy, NH2 or 1-3C acylamino); thienylmethyl or furylmethyl (both opt. ring-substd. by 1-3C alkyl) or cyclohexylmethyl; R4 = 1-20C alkyl or 2-20C alkenyl (contg. 1-3 double bonds), both opt. interrupted by O or S, phenyl(1-4C)alkyl, phenyl(2-4C)alkenyl, phenyl (opt. substd. by 1 or 2 of 1-3C alkyl, Ph, OH, 1-3C alkoxy, NH2, 1-3C acylamino, NO2, CN or halo), cyclohexyl, cyclohexyl(1-4C)alkyl or cyclohexyl(2-4C)alkenyl; R5, R6 = H or Ph; <= 6C alkyl, alkenyl or alkynyl (all opt. substd. by Ph), with at least one satd. C between N and the multiple bond; or NR5R6 = satd. monocyclic 5-7 membered heterocycle opt. contg. a further O, S or N. |