http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-202014010421-U1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4c6a2eb66d07fad39d708e5a36c9350 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-22 |
| filingDate | 2014-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-202014010421-U1 |
| titleOfInvention | Human goals |
| abstract | A human anti-VEGF A ligand for use in a method of treating or reducing the risk of retinopathy in a human, comprising administering the ligand to a human, wherein the human anti-VEGF A ligand specifically binds to a human VEGF. A, which is expressed by a VEGF-A nucleotide sequence comprising an SNP selected from the group consisting of: rs699947; rs833061; rs2010963; rs3025039; rs699946; rs2146323; rs1413711; rs833068; rs833069; rs3025000 and rs1570360; wherein the ligand comprises a human gamma-1 heavy chain constant region comprising an amino acid selected from the group consisting of: an Asp corresponding to position 204 of SEQ ID NO: 42 and a Leu corresponding to position 206 of SEQ ID NO: 42; and where man includes (i) a human heavy chain constant region IGHG1 * 01 gene segment or human expressing antibodies comprising human gamma-1 heavy chain constant regions comprising the selected amino acid, and (ii) a VEGF-A nucleotide sequence comprising the selected SNP. |
| priorityDate | 2013-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 361.