| abstract |
Use of enamine derivatives of formula (R<3>)(R<4>NH)C=C(R<1>)(R<2>) (I) as UV filters in cosmetic and pharmaceutical preparations for protection of hair or skin against sun-radiation, alone or in combination with UV absorbers is new: R<1> = COOR<5>, COR<5>, CONR<5>R<6>, CN, SO2R<5>, SO2OR<5> or P(=O)OR<7>OR<8>; R<2> = COOR<6>, COR<6>, CONR<5>R<6>, CN, SO2R<6>, SO2OR<6> or P(=O)OR<7>OR<8>; R<3> = H, or optionally substituted aliphatic, cycloaliphatic, arylaliphatic or aromatic residue with up to 18C; R<4> = optionally substituted 5-12C aromatic or heteroaromatic residue; and R<5>, R<6> = H or aliphatic, arylaliphatic, cycloaliphatic, or optionally substituted aromatic with up to 18C; or R<3>-R<8> together with their bonded carbon atoms may form a 5-6 membered ring which may be further annelated. |