| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c6624209e73a6f30362afa2e9ffcf0a0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 |
| filingDate |
2022-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53d5a9a835c697f0c84fff254e2ff321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f4e0f519e613459da5a620abfb99830
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d1049f25e0fa2f3ef334c1fbcc10eac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40e0b2a73575be3f0100195838d8125b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51a9bf7305b6d5e80a82048a96f3748e |
| publicationDate |
2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114618015-A |
| titleOfInvention |
Collagen-containing PHA microspheres and preparation method and use thereof |
| abstract |
The invention discloses a collagen-containing PHA microsphere and a preparation method and application thereof. The method of the present invention comprises adding polyvinyl alcohol to water to prepare a first liquid phase, and the concentration of polyvinyl alcohol in the first liquid phase is controlled to be 0.1-95% by weight; adding a fat-soluble polymer to an organic solvent to prepare a second liquid phase phase, the concentration of the fat-soluble polymer in the second liquid phase is controlled to be 0.1-100 mg/mL; the first liquid phase and the second liquid phase are mixed at a volume ratio of 3-15:1 to prepare microspheres. The collagen-containing PHA microspheres of the present invention solve the problems of low cell adhesion, easy agglomeration, adhesion and insufficient histocompatibility of the microspheres, and have the advantages in the fields of medical cosmetic filling, cell culture and implantation of medical devices. Broad application prospects. |
| priorityDate |
2022-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |