http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114315784-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6fec0bef233499f3d091ecb58997ae7e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-82 |
filingDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fef37393da790c5adeb61bab86e33e93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3070ef073259038a7bded531fc95d1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36cc64d13ca896cced06791a96781138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3ca6cf6146047d0d75babc9e02a0da8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42de6d0a9580bd3e106c5a3d1ee93988 |
publicationDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114315784-A |
titleOfInvention | A kind of histidine-labeled fluorescent probe and its preparation method and application |
abstract | A histidine-labeled fluorescent probe and its preparation method and application. The invention discloses a histidine-labeled fluorescent compound based on a rhodamine B derivative and a preparation method and application thereof. The fluorescent compound Rho-IDA can chelate different metal ions, and the fluorescent probe derivative Rho-IDA-CoII obtained by chelating divalent cobalt ions has the function of specifically labeling the histidine tag fusion protein. The fluorescent probe of the invention has the advantages of simple synthesis method, small molecular weight, and excitation and emission wavelengths in the near-infrared region. When applied to biological imaging, it can reduce the interference of fluorescent impurities in the background environment; at the same time, it can quickly and specifically label and stain the histidine-tagged fusion protein in the gel, providing a reliable research tool for related biochemical research. |
priorityDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 285.