abstract |
The invention relates to a method for preparing benzimidazo[2,1-a]isoquinoline-6(5H)-ketone compounds. In the method, by adding N-methacryloyl-2-phenylbenzimidazole compounds, nitrile compounds/acetone/tert-butyl nitrite, catalyst, oxidant and solvent into Schlenk reaction flask, at a certain temperature, air atmosphere Under stirring reaction, the cyanoalkyl/ketone skeleton/nitro-substituted benzimidazo[2,1-a]isoquinoline-6(5H)-ketone compound is obtained. |