| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate |
2020-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb00921be36127ee2fe1b3e13311d3ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8fe9dc4c29b3e985366cb96b201460c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2295a31db9e5a4f5a19fae0239be59ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_925778873b86b432be5f01e69a7b1d5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2fc3928d323f766f190be7066293832
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32d1d662a56800c3c0235c8a0a72f842 |
| publicationDate |
2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113853384-A |
| titleOfInvention |
Novel design of a protein switch for the tuneable control of protein degradation |
| abstract |
Disclosed herein are non-naturally occurring cage polypeptides, kits and degradation determinants LOCKR comprising the cage polypeptides, wherein the cage polypeptides comprise: (a) a helical bundle comprising 2 to 7 a-helices, wherein the helical bundle comprises: (i) a structural region; and (ii) a latching region, wherein the latching region constitutes a degradation determinant located within the latching region, wherein the structural region interacts with the latching region to prevent activity of the degradation determinant; and (b) an amino acid linker connecting each alpha-helix. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114058641-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114058641-B |
| priorityDate |
2019-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |