http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113501773-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 |
| filingDate | 2021-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113501773-B |
| titleOfInvention | Beta-ketone sulfoxide derivative of carboxylic acid drugs and preparation method and application thereof |
| abstract | The invention provides a beta-ketone sulfoxide derivative of carboxylic acid drugs, a preparation method and application thereof, belonging to the technical field of organic synthesis. Using acyl chloride derivatives of carboxylic acids as raw materials in CaC 2 Preparation of beta-ketosulfoxide derivatives of this class of drugs in the Presence of TEA, in one aspect, in CaC 2 Under the coexistence of TEA, the yield of the prepared beta-keto sulfoxide derivative is up to 49-64%, and the beta-keto sulfoxide derivative is green and environment-friendly, mild in reaction process and simple to operate. On the other hand, the prepared beta-keto sulfoxide derivative is used as a medicine for treating respective indications, has less stimulation to intestines and stomach after entering a human body, and has the advantages of high activity, low toxicity and high added value. |
| priorityDate | 2020-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.