| abstract |
The invention discloses a method for preparing aryl thioamide compounds: under the protection of inert gas, aryl methanol is used as a substrate, sublimed sulfur is used as a sulfur source, and an alkali metal complex formed by combining an alkali metal salt and a ligand is used. The compound is the catalyst, the base is the promoter, the formamide is the solvent and the amine source, and the reaction is stirred for 6 to 12 hours at the reaction temperature of room temperature to 60 °C; . The invention adopts cheap and easy-to-obtain aryl methanol as a substrate to carry out three-component reaction to prepare corresponding thioamide compounds; the method of the invention is used to prepare aryl thioamide compounds, which has the advantages of simple process, high yield, Less pollution, safety and environmental protection, green and mild technology advantages. |