| abstract |
The invention belongs to technical field of organic synthesis, disclose a kind of preparation method of arylthio amide.This method is without transition metal-catalyzed, and under alkaline condition, using fragrant alkynes, elemental sulfur and amide as raw material, corresponding arylthio amide is generated by three component reactions.The synthetic system scope of application is wider, compatible Terminal Acetylenes and interior alkynes, while compatible formamide, acetamide and propanamide derivative.Raw material economics is easy to get, simple for process, and wide application range of substrates, yield is higher, is suitble to industrial application. |