http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112442091-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2019-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112442091-B |
| titleOfInvention | Platinum compounds targeting replication protein A |
| abstract | The invention discloses a platinum-based compound targeting replication protein A, a series of platinum-based anti-tumor compounds synthesized by combining tetravalent cisplatin with an RPA (replication protein A) small molecule inhibitor through an axial hydroxyl position and introducing an aliphatic hydrocarbon chain. The platinum-based antitumor compound itself has the advantages of inhibiting RPA activity and tumor-specific selection, thus showing an antitumor activity superior to that of classic platinum-based drugs, and showing the potential to overcome clinical platinum-based drug resistance. |
| priorityDate | 2019-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.