| abstract |
The invention discloses a preparation method of an allyl nitrile compound. The preparation method comprises the following steps: in a solvent, in the presence of a copper catalyst, a bisoxazoline ligand and the compound shown in the formula A, an allyl compound containing a structural fragment shown in the formula II and a cyanation reagent shown in the formula III are subjected to substitution reaction shown in the following formula, so as to obtain an allyl nitrile compound containing a structural fragment shown in the formula I. The method has the characteristics of high yield, wide substrate universality, good functional group compatibility, mild reaction conditions and simple operation. |