| abstract |
The invention discloses a fluorine nitrogen type amination reagent, its preparation method and application. The application comprises the following steps: under the protection of gas, in an organic solvent, under the action of a copper catalyst, a dinitrogen ligand and a base, the fluorine nitrogen type amination reagent shown in formula I, the fluorine nitrogen type amination reagent shown in formula II The compound and the compound shown in formula III are reacted as shown below to prepare the compound shown in formula IV. Under the action of copper catalyst and dinitrogen ligand, the fluorine-nitrogen type amination reagent of the present invention takes olefin as a substrate, and through the asymmetric amine arylation reaction of olefin, obtains optical Active 2,2-diarylethanamines. |