Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-02 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate |
2020-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2021-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-112043713-B |
titleOfInvention |
Application of betulinic acid derivative in preparing medicine for treating nerve injury diseases |
abstract |
The invention belongs to the field of medicines, and discloses an application of betulinic acid derivatives or pharmaceutically acceptable salts thereof in preparing medicines for treating nerve injury diseases. The invention successfully carries out structural modification on the betulinic acid by utilizing a microbial transformation technology to obtain a plurality of novel compounds, and in-vitro nerve cell injury protection tests prove that the compounds have better nerve cell protection activity, can be used as active ingredients of medicaments for treating neurodegenerative diseases, traumatic brain injury and stroke, and have wide application. |
priorityDate |
2020-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |