| abstract |
The present invention belongs to the technical field of medicine, in particular, relates to a class of caffeoyl-substituted pentacyclic triterpene derivatives represented by formula I and its preparation for the prevention and treatment of cerebral ischemia, glucose deficiency, and hypoxia-induced brain injury and / or use in drugs or health products for abnormal neurological function and / or cognitive dysfunction. It has been confirmed by experiments that this type of compound has the function of protecting nerve cells under conditions of lack of sugar and hypoxia, and has a significant improvement effect on nerve function damage induced by cerebral ischemia. It is expected to be developed for the prevention and treatment of cerebral ischemia, low sugar and hypoxia Induced brain injury and drugs to improve corresponding neurobehavioral function. |