abstract |
The present invention relates to 3'3'-cyclic dinucleotides (I) modified with 3'-phosphonoalkyl bonds and derivatives thereof or pharmaceutically acceptable salts thereof, which can modulate the activity of STING adaptor proteins, wherein , L 1 is ‑O‑ or ‑K‑C(R 6 R 7 )‑; L 2 is ‑K‑C(R 6 R 7 )‑. |