http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111825614-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 |
| filingDate | 2020-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111825614-B |
| titleOfInvention | A kind of preparation method of gliquinone intermediate |
| abstract | The invention belongs to the technical field of pharmaceutical synthesis chemistry, in particular to a method for preparing an intermediate of glitazone. The technical scheme of the present invention is as follows: Step 1. Add compound II and compound III into the reaction kettle at a certain molar ratio, add a hydrophilic solvent 5-10 times the mass of compound II, seal, and the reaction temperature is 150-170 ℃ ℃; step 2. After the reaction material in step 1 is cooled to room temperature, gradually open the air valve, centrifuge the reaction feed liquid, wash with the reaction solvent, and dry at 60 ℃ to obtain the intermediate I of Gliquidone. The present invention provides an energy-saving and safe preparation method of gliquidone intermediate I. |
| priorityDate | 2020-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.