http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235263-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate | 2020-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111235263-B |
| titleOfInvention | Target gene for diagnosis and treatment of osteoarthritis |
| abstract | The invention provides a target gene for diagnosing and treating osteoarthritis, wherein the specific target gene is RP1-45I4.3, the expression level of RP1-45I4.3 is detected, the RP1-45I4.3 is found to be remarkably up-regulated in a sample of a patient, and the RP1-45I4.3 is used as a variable for statistical analysis, so that the target gene has a higher area under a curve, and the RP1-45I4.3 can be used as a detection target to effectively distinguish osteoarthritis patients from normal people; the invention simultaneously detects the influence of RP1-45I4.3 on the proliferation and the apoptosis of chondrocytes by changing the expression level of RP1-45I4.3, finds that the reduction of the expression of RP1-45I4.3 can promote the proliferation of cells and inhibit the apoptosis of cells, and indicates that RP1-45I4.3 can be used as a new target for treating osteoarthritis. |
| priorityDate | 2020-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 191.