http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110055324-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d8a6eb8355272d02e1b66f0ac3ddb96 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
| filingDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3264389ecdb4e41fc7e1b5bfc6457618 |
| publicationDate | 2019-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110055324-A |
| titleOfInvention | A method of using lncRNA come diagnosing and treating tumor of prostate |
| abstract | The present invention relates to field of molecular detection more particularly to the methods of lncRNA detection and treatment prostate cancer (PCa).The present invention provides the diagnosing and treating target spots that PCAT3/PCAT9-miR-203-SNAI2 axis can be used as PCa.Specifically, inhibiting the proliferation of cell by knocking out PCAT3 in androgen-dependent cell LNCaP and 22Rv1 and PCAT9, infecting, spread, angiogenesis and deterioration.PCAT3 and PCAT9 all inhibit miR-203 express, alleviate the crucial adjuster that SNA12(miR-203 is directly targeted Epithelial and stromal transition) expression inhibiting effect.The silencing of miR203 or the ectopic expression of SNA12 reduce the inhibiting effect of PCAT3 and PCAT9 cell Proliferation and migration in vitro, and the growth of heterograft in vivo. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235263-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235263-A |
| priorityDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.