Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b680abcda15bb47da291642227f27e4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
filingDate |
2019-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_714c9280c75a159ab1f6989a172c8a55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a2a95d31019f1d7dc21f248d430dd14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1880b5a56f305a8d64551b8cb9e58228 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b77658d53f3200c96f3a8c1f4c0f7f21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0d3994c915eecfeeac6df0f7873a977 |
publicationDate |
2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-110511974-A |
titleOfInvention |
A kind of fermentation method that improves erythromycin fermentation titer |
abstract |
The invention relates to a fermentation method for increasing the fermentative titer of erythromycin. The fermentation method adopts Streptomyces rubrum as the fermentation strain and is produced in a two-stage fermentation mode consisting of seed culture and fermentation culture. And the formula structure of the fermentation medium eliminates the use of soybean cake powder, adds sodium nitrate solution as a nitrogen source, and introduces the trace element cobalt, which improves the oxygen supply conditions during the fermentation process and reduces the energy consumption of oxygen supply. Enhance the vigor of bacteria, prolong the secretion period of erythromycin, and improve the fermentation level of erythromycin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112410395-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112410395-A |
priorityDate |
2019-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |