http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110467603-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 2019-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110467603-B |
| titleOfInvention | Pleuromutilin derivative with piperazine and 1,2, 3-triazole secondary amine side chain as well as preparation and application thereof |
| abstract | The invention belongs to the field of medicinal chemistry, and particularly relates to a pleuromutilin derivative with piperazine and 1,2, 3-triazole secondary amine side chains, and preparation and application thereof. The pleuromutilin derivative with piperazine and 1,2, 3-triazole secondary amine side chains is a compound of formula 2 or pharmaceutically acceptable salt thereof, and a solvent compound, enantiomer, diastereoisomer, tautomer or mixture of the compound of formula 2 or pharmaceutically acceptable salt thereof in any proportion, including racemic mixture: the compound not only has good in-vitro antibacterial activity, but also has the advantage of lower preparation cost than valnemulin and ritamolin, so the compound is particularly suitable to be used as a novel antibacterial drug for preventing and treating bacterial infectious diseases of human beings or animals, especially infectious diseases caused by drug-resistant staphylococcus aureus. |
| priorityDate | 2019-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 131.