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filingDate 2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_495de4a336100f7c8381c77334a24404
publicationDate 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110272630-A
titleOfInvention A kind of silk fibroin porous three-dimensional material and preparation method thereof
abstract The invention discloses a porous three-dimensional silk fibroin material. The material uses silkworm sericin and tussah silk fibroin as raw materials. The preparation method of the porous three-dimensional silk fibroin material includes firstly preparing silkworm sericin, Tussah silk fibroin protein mixed solution; then add organic additives to the mixed solution; then put the mixed solution in a specially shaped mold, place the bottom of the mold in a liquid nitrogen bath for qualitative and directional freezing, and wait for the ice crystals to grow completely from bottom to top , the mold and samples were transferred to liquid nitrogen for storage at low temperature. The samples stored at low temperature were then transferred to a freeze dryer for drying. Finally, the dried samples were treated with methanol and deionized water successively, and then freeze-dried again. The manufacturing process of the porous silk fibroin three-dimensional material and the preparation method thereof is simple, and the porosity and biocompatibility of the manufactured silk fibroin porous three-dimensional material can be effectively improved, and can be degraded in a relatively short time.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111671980-A
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priorityDate 2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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