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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06
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filingDate 2019-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110118836-B
titleOfInvention Method for determining genotoxic impurities in rivaroxaban by high performance liquid chromatography
abstract The invention provides a method for determining genotoxic impurities in rivaroxaban by high performance liquid chromatography, wherein octadecylsilane chemically bonded silica is used as a filler for a chromatographic column; the mobile phase adopts water and acetonitrile with the volume ratio of 69-71: 29-31, and the pH value of the water is adjusted to 2.5 +/-0.1; the detection wavelength is 245 nm-255 nm and/or 225 nm-235 nm. The method for determining the genotoxic impurities in rivaroxaban by using the high performance liquid chromatography provided by the invention can better control the quality of rivaroxaban.
priorityDate 2019-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.