http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110118836-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-047 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2019-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110118836-B |
titleOfInvention | Method for determining genotoxic impurities in rivaroxaban by high performance liquid chromatography |
abstract | The invention provides a method for determining genotoxic impurities in rivaroxaban by high performance liquid chromatography, wherein octadecylsilane chemically bonded silica is used as a filler for a chromatographic column; the mobile phase adopts water and acetonitrile with the volume ratio of 69-71: 29-31, and the pH value of the water is adjusted to 2.5 +/-0.1; the detection wavelength is 245 nm-255 nm and/or 225 nm-235 nm. The method for determining the genotoxic impurities in rivaroxaban by using the high performance liquid chromatography provided by the invention can better control the quality of rivaroxaban. |
priorityDate | 2019-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.