http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109942499-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109942499-B |
| titleOfInvention | Quinazoline derivative and preparation method and application thereof |
| abstract | The invention relates to quinazoline derivatives, a preparation method and application thereof. The quinazoline derivative has The quinazoline derivative takes gefitinib as a positive control, and the result shows that the quinazoline derivative has good activity compared with gefitinib; compared with the lead compound OTS514, the activity is equivalent, and the derivative is further modified for PBK/TOPK inhibitor and has higher reference and reference value for finding new antitumor drug candidates. The invention also provides a preparation method of the quinazoline derivative and application of the quinazoline derivative in preparation of PBK/TOPK inhibitors and anticancer drugs. |
| priorityDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.