abstract |
The invention discloses a 4-[4-(2-substituted aminoacetamido)anilino]quinazoline derivative and its preparation and application. The 4-[4-(2-substituted aminoacetamido)anilino ] quinazoline derivatives have the following general structural formula (I), in the general structural formula (I), R is in dimethylamino, diethylamino, dipropylamine, morpholinyl or m-toluidine One; X is H or Cl. The 4-[4-(2-substituted aminoacetamido)anilino]quinazoline derivatives of the invention can be used to prepare medicines for preventing or treating human lung cancer or human breast cancer, and have good anticancer activity. |