http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109896999-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 |
| filingDate | 2019-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109896999-B |
| titleOfInvention | Synthesis method of pyrazolone compound containing adjacent tertiary carbon-quaternary carbon chiral center |
| abstract | The invention provides a synthesis method of pyrazolone compounds containing adjacent tertiary carbon-quaternary carbon chiral centers, which is shown in a formula (3). in a water-oil two-phase system, 2- (aryl (p-toluenesulfonyl) methyl) phenol shown in a raw material formula (1) and 4-benzyl pyrazolone shown in a formula (2) react under the action of an acid binding agent and a chiral catalyst, TLC (thin layer chromatography) tracking monitoring is carried out until the reaction is complete, and then reaction liquid is subjected to post-treatment to obtain the product pyrazolone compounds containing adjacent tertiary carbon-quaternary carbon chiral centers, which is shown in the formula (3); the invention is widely applied to the fields of pesticides and medicines, and has the advantages of wide application prospect, mild synthesis conditions, high yield, good asymmetric selectivity, wide range of reaction substrates, cheap and easily-obtained reaction reagents and strong operability. |
| priorityDate | 2019-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.