http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109464703-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-26 |
| filingDate | 2018-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109464703-B |
| titleOfInvention | Bone repair material and preparation method and application thereof |
| abstract | The invention belongs to the field of biomedical materials containing active protein and the field of regenerative medicine, and particularly provides a bone repair material which comprises modified chitosan, gelatin and rH-BMP 2. The material can be used for repairing bone injury. The bone repair material comprises the following components in percentage by mass: rH-BMP2 (1% -10%); 20 to 70 percent of modified chitosan; gelatin (20% -70%). The invention takes the allyl trimethyl ammonium chloride or acrylamide modified chitosan and gelatin as the slow release carrier to realize great progress in degradation/drug release time and obviously reduce the anaphylaxis. The effect which is obviously superior to that of chitosan and the prior similar material is obtained in both in-vitro release experiments and animal experiments. The cytotoxicity test also preliminarily proves the safety of the compound. |
| priorityDate | 2018-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.