http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109293506-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B41-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-31 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B41-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-757 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-31 |
| filingDate | 2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109293506-B |
| titleOfInvention | Method for continuously preparing chiral alpha-hydroxy-beta-dicarbonyl compound by visible light catalytic molecular oxygen oxidation through microreactor |
| abstract | The invention belongs to the field of flow chemistry, and provides a method for continuously preparing a chiral alpha-hydroxy-beta-dicarbonyl compound by visible light catalytic molecular oxygen oxidation through a microreactor. The method uses chiral cinchona alkaloid derivative quaternary ammonium salt as a chiral phase transfer catalyst, and realizes the continuous oxidation of a beta-dicarbonyl compound by visible light activated gas molecular oxygen catalysis through a microreactor in the presence of an organic photosensitizer to prepare the chiral alpha-hydroxy-beta-dicarbonyl compound. The method has the advantages of high efficiency, low carbon, sustainability and continuity. The method can realize the substrate conversion rate of nearly 100 percent within 1-10 min of reaction residence time, the product selectivity is higher than 95 percent, the product stereoselectivity is higher than the ee value of 80 percent, the reaction is green, the environmental burden is low, the continuity is realized, and the method has the advantages of large-scale production and low cost. |
| priorityDate | 2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.