| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fa7a89b8d8bc79f53cd249e5422d51c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1369
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0793 |
| filingDate |
2018-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dcbe6f0c79fa89b01c06de9b9772371 |
| publicationDate |
2019-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109266610-A |
| titleOfInvention |
Method for promoting differentiation of mesenchymal stem cells into neurons |
| abstract |
The invention discloses a method for promoting differentiation of mesenchymal stem cells into neurons, comprising the following steps: 1) preparing human mesenchymal stem cells and subculturing them; 2) making the human mesenchymal stem cells after subculture in a differentiation medium Medium differentiated adult mesenchymal stem cells - neurospheres; 3) differentiated human mesenchymal stem cells - neurospheres into neurons in an induction medium. Differentiation of neurons into neurons was induced by the addition of neurotrophic factors in the induction medium. The results showed that cells expressing mature neural markers (MAP2ab) and immature neurological markers (β-tubulin III) were significantly improved relative to the blank control. . The method of the present invention provides a certain direction for the promotion of new treatments for spinal cord injury repair. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022257001-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113278624-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112899234-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111269887-A |
| priorityDate |
2018-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |