http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109212093-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109212093-B |
| titleOfInvention | HPLC detection method of valganciclovir hydrochloride intermediate condensation compound isomer |
| abstract | The invention belongs to the field of pharmaceutical analysis, and particularly discloses an HPLC (high performance liquid chromatography) detection method for an intermediate condensation product enantiomer of valganciclovir hydrochloride, which uses a chiral chromatographic column with cellulose-tris (4-chloro-3-methylphenyl carbamate) coated silica gel as a filler, and uses a mixed solution of water and nitriles as a mobile phase, wherein the column temperature is 10-20 ℃, the flow rate is 0.4-0.6 ml/min, and the wavelength is 250-260 nm. The method realizes effective separation of four isomers of the valganciclovir hydrochloride intermediate condensation compound, has good detection result accuracy, high sensitivity, simple and convenient operation, low cost and short analysis time, and provides guarantee for quality control of the valganciclovir hydrochloride intermediate condensation compound. |
| priorityDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.