http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104749286-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2015-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104749286-B |
| titleOfInvention | A kind of analyzing detecting method of valganciclovir hydrochloride impurity |
| abstract | The invention belongs to technical field of analytical chemistry, specifically disclose a kind of HPLC analyzing detecting method of valganciclovir hydrochloride impurity, more particularly, it relates to a kind of analysis detection guanine, GCV, methoxy guanine, 1 N methylvaline ester of GCV, monovinylphenyl GCV, monochloro are for GCV or the method containing the medicine or its preparation of impurity in above-mentioned 6.The mobile phase in performance liquid chromatographic column of the solution to be measured injection with phenyl silane bonded silica gel as filler, being constituted with chromatographically pure organic solvent with the inorganic salt solution containing amine is rinsed and is separated, then detected with ultraviolet light analysis.This method creatively adds certain density ammonium acetate or ammonium formate first in mobile phase, the difficult problem that main peak and impurity peaks and other impurities peak between separate difficulty is thoroughly solved, easy to operate, separating degree is big, sensitivity is high, accuracy is good, by literature search, there is no similar document report. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109212093-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109212093-A |
| priorityDate | 2015-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.