http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108721321-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
filingDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108721321-B |
titleOfInvention | Tumor-targeted nano diagnosis and treatment agent, preparation method and application thereof |
abstract | A tumor-targeted nano diagnosis and treatment agent comprises silica nanoparticles with cavities and mesoporous channels and transition metal carbonyl compounds loaded in the cavities and the mesoporous channels of the silica nanoparticles. The invention also provides a preparation method and application of the tumor-targeted nano diagnosis and treatment agent. According to the invention, the transition metal carbonyl compound is loaded in the silicon dioxide nanoparticles by a vacuum nano-casting method, so that the preparation process is simple, the cost is low, and the loading efficiency of the transition metal carbonyl compound is high. In addition, the nano diagnosis and treatment agent has passive targeting tumor transportation, CO release in response of tumor parts and MRI imaging monitoring of CO release, so that the nano diagnosis and treatment agent for treating tumors is a noninvasive, low-toxicity and green treatment mode. |
priorityDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.