http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108484760-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02 |
| filingDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108484760-B |
| titleOfInvention | An anti-ricin immunoglobulin F (ab')2And method for preparing the same |
| abstract | The invention discloses an anti-ricin immunoglobulin F (ab') 2 and a preparation method thereof. The invention provides a method for preparing anti-ricin immunoglobulin F (ab') 2, which comprises the following steps: immunizing animals by using immunogen to prepare a ricin IgG antibody, and removing an Fc segment of the ricin IgG antibody to obtain anti-ricin immunoglobulin F (ab') 2; the antigens of the immunogen are as follows: 1) a low-or attenuated ricin mutant or recombinant protein thereof; 2) a DNA molecule encoding the low-toxicity or attenuated ricin mutant or recombinant protein thereof, or a vector, an expression cassette, a recombinant bacterium or a recombinant virus expressing the DNA molecule; 3) detoxified natural ricin. The invention utilizes nontoxic or low toxic ricin antigen to immunize healthy animals, generates antiserum with high-efficiency neutralization ricin, and has specific protection effect on the treatment and prevention of ricin. |
| priorityDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 225.